Fosforibozilformilglicinamidinska ciklo-ligaza

Fosforibozilformilglicinamidinska ciklo-ligaza
Identifikatori
EC broj6.3.3.1
CAS broj9023-53-4
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

Fosforibozilformilglicinamidinska ciklo-ligaza (EC 6.3.3.1, fosforibozilaminoimidazolna sintetaza, AIR sintetaza, 5'-aminoimidazol ribonukleotid sintetaza, 2-(formamido)-1-N-(5-fosforibozil)acetamidin ciklo-ligaza (formira ADP)) je enzim sa sistematskim imenom 2-(formamido)-N1-(5-fosforibozil)acetamidin ciklo-ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + 2-(formamido)-N1-(5-fosfo-D-ribozil)acetamidin {\displaystyle \rightleftharpoons } ADP + fosfat + 5-amino-1-(5-fosfo-D-ribozil)imidazol

Reference

  1. ^ Levenberg, B. & Buchanan, J.M. (1957). „Properties of the purines. XII. Structure, enzymatic synthesis, and metabolism of 5-aminoimidazole ribotide”. J. Biol. Chem. 224: 1005—1018. PMID 13405929. 
  2. ^ Levenberg, B. & Buchanan, J.M. (1957). „Biosynthesis of the purines. XIII. Structure, enzymatic synthesis, and metabolism of (α-N-formyl)-glycinamidine ribotide”. J. Biol. Chem. 224: 1018—1027. PMID 13405930. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

  • Phosphoribosylformylglycinamidine+cyclo-ligase на US National Library of Medicine Medical Subject Headings (MeSH)
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Enzimi: CO CS i CN ligaza (EC 6.1-6.3)
6.1: Ugljenik-kiseonik6.2: Ugljenik-sumpor6.3: Ugljenik-azot
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Teme
Tipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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