GMP sintaza (hidrolizacija glutamina)
GMP sintaza (hidrolizacija glutamina) | |||||||||
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Identifikatori | |||||||||
EC broj | 6.3.5.2 | ||||||||
CAS broj | 37318-71-1 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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GMP sintaza (hidrolizacija glutamina) (EC 6.3.5.2, GMP sintetaza (glutaminska hidroliza), guanilatna sintetaza (glutaminska hidroliza), guanozin monofosfatna sintetaza (glutaminska hidroliza), ksantozin 5'-fosfatna amidotransferaza, guanozin 5'-monofosfatna sintetaza) je enzim sa sistematskim imenom ksantozin-5'-fosfat:L-glutamin amido-ligaza (formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + XMP + L-glutamin + H2O AMP + difosfat + GMP + L-glutamat
Reference
- ^ Abrams, R. & Bentley, M. (1959). „Biosynthesis of nucleic acid purines. III. Guanosine 5′-phosphate formation from xanthosine 5′-phosphate and L-glutamine”. Arch. Biochem. Biophys. 79: 91—110.
- ^ Lagerkvist, U. (1958). „Biosynthesis of guanosine 5′-phosphate. II. Amination of xanthosine 5′-phosphate by purified enzyme from pigeon liver”. J. Biol. Chem. 233: 143—149. PMID 13563458.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- GMP+synthase+(glutamine-hydrolysing) на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- Glutamin sintetaza
- Ubikvitinska ligaza
- Kulin
- Von Hipel–Lindau tumor supresor
- UBE3A
- Mdm2
- Kompleks promovisanja anafaze
- UBR1
- Glutationska sintetaza
- CTP sintaza
- Adenilosukcinatna sintaza
- Argininosukcinatna sintaza
- Holokarboksilazna sintaza
- GMP sintaza
- Asparagin sintaza
- Karbamoil fosfat sintaza
- I
- II
- Glutamat-cisteinska ligaza