Magnezijumska helataza

Magnezijumska helataza
Identifikatori
EC broj6.6.1.1
CAS broj9074-88-8
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
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PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
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NCBIproteini

Magnezijumska helataza (EC 6.6.1.1, protoporfirin IX magnezijum-helataza, protoporfirin IX Mg-helataza, magnezijum-protoporfirin IX helataza, magnezijum-protoporfirin helataza, magnezijum-helataza, Mg-helataza, Mg-protoporfirin IX magnezio-lijaza) je enzim sa sistematskim imenom Mg-protoporfirin IX magnezijum-lijaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + protoporfirin IX + Mg2+ + H2O {\displaystyle \rightleftharpoons } ADP + fosfat + Mg-protoporfirin IX + 2 H+

Ovaj enzim posreduje prvi korak u biosintezi hlorofila.

Reference

  1. ^ Walker, C.J. & Weinstein, J.D. (1991). „In vitro assay of the chlorophyll biosynthetic enzyme Mg-chelatase: resolution of the activity into soluble and membrane-bound fractions”. Proc. Natl. Acad. Sci. USA. 88: 5789—5793. PMID 11607197. 
  2. ^ Walker, C.J. & Willows, R.D. (1997). „Mechanism and regulation of Mg-chelatase”. Biochem. J. 327: 321—333. PMID 9359397. 
  3. ^ Fodje, M.N., Hansson, A., Hansson, M., Olsen, J.G., Gough, S., Willows, R.D. and Al-Karadaghi, S. (2001). „Interplay between an AAA module and an integrin I domain may regulate the function of magnesium chelatase”. J. Mol. Biol. 311: 111—122. PMID 11469861. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • Magnesium+chelatase на US National Library of Medicine Medical Subject Headings (MeSH)
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Enzimi: Fosforno estarske i azot-metalne ligaze (EC 6.5-6.6)
6.5: Fosforni estar6.6: Azot-metal
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Teme
Tipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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