Biyoortogonal kimya
Biyoortogonal kimya, yaşayan bir sistemde, sistemin doğal biyokimyasal süreçleriyle çakışmadan gerçekleşen herhangi bir kimyasal reaksiyondur.[1][2][3] Terim, Carolyn R. Bertozzi tarafından 2003 yılında ortaya atılmıştır.[4][5]
Kaynakça
- ^ Sletten, Ellen M.; Bertozzi, Carolyn R. (2009). "Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality". Angewandte Chemie International Edition. 48 (38). ss. 6974-6998. doi:10.1002/anie.200900942. PMC 2864149 $2. PMID 19714693.
- ^ Prescher, Jennifer A.; Dube, Danielle H.; Bertozzi, Carolyn R. (2004). "Chemical remodelling of cell surfaces in living animals". Nature. 430 (7002). ss. 873-877. Bibcode:2004Natur.430..873P. doi:10.1038/nature02791. PMID 15318217.
- ^ Prescher, Jennifer A; Bertozzi, Carolyn R (2005). "Chemistry in living systems". Nature Chemical Biology. 1 (1). ss. 13-21. doi:10.1038/nchembio0605-13. PMID 16407987.
- ^ Hang, Howard C.; Yu, Chong; Kato, Darryl L.; Bertozzi, Carolyn R. (9 Aralık 2003). "A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation". Proceedings of the National Academy of Sciences (İngilizce). 100 (25). ss. 14846-14851. Bibcode:2003PNAS..10014846H. doi:10.1073/pnas.2335201100. ISSN 0027-8424. PMC 299823 $2. PMID 14657396.
- ^ Sletten, Ellen M.; Bertozzi, Carolyn R. (2011). "From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions". Accounts of Chemical Research. 44 (9). ss. 666-676. doi:10.1021/ar200148z. PMC 3184615 $2. PMID 21838330.
