SKIL |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | | |
Ідентифікатори |
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Символи | SKIL, SNO, SnoA, SnoI, SnoN, SKI-like proto-oncogene, SKI like proto-oncogene |
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Зовнішні ІД | OMIM: 165340 MGI: 106203 HomoloGene: 3948 GeneCards: SKIL |
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Онтологія гена |
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Молекулярна функція | • DNA binding • GO:0001106 transcription corepressor activity • protein domain specific binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding • SMAD binding • chromatin binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0032403 protein-containing complex binding |
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Клітинна компонента | • цитоплазма • PML body • нуклеоплазма • Акросома • клітинне ядро • GO:0009327 protein-containing complex |
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Біологічний процес | • positive regulation of extrinsic apoptotic signaling pathway via death domain receptors • response to cytokine • lymphocyte homeostasis • GO:1904576 response to antibiotic • GO:1901227 negative regulation of transcription by RNA polymerase II • blastocyst formation • positive regulation of axonogenesis • protein homotrimerization • lens fiber cell differentiation • positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage • Сперматогенез • protein heterotrimerization • response to growth factor • skeletal muscle tissue development • negative regulation of BMP signaling pathway • transforming growth factor beta receptor signaling pathway • negative regulation of transforming growth factor beta receptor signaling pathway • neuron development • negative regulation of cell differentiation |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | NM_001145097 NM_001145098 NM_001248008 NM_005414 |
| NM_001039090 NM_001271772 NM_011386 NM_001398558 NM_001398559
| NM_001398560 |
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RefSeq (білок) | | NP_001138569 NP_001138570 NP_001234937 NP_005405 |
| NP_001034179 NP_001258701 NP_035516 NP_001385487 NP_001385488
| NP_001385489 |
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Локус (UCSC) | Хр. 3: 170.36 – 170.4 Mb | Хр. 3: 31.15 – 31.18 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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