SCN2B |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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5FEB, 5FDY |
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Identifiers |
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Aliases | SCN2B, ATFB14, sodium voltage-gated channel beta subunit 2 |
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External IDs | OMIM: 601327; MGI: 106921; HomoloGene: 3373; GeneCards: SCN2B; OMA:SCN2B - orthologs |
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Gene location (Human) |
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![Chromosome 11 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png) | Chr. | Chromosome 11 (human)[1] |
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| Band | 11q23.3 | Start | 118,162,806 bp[1] |
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End | 118,176,639 bp[1] |
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Gene location (Mouse) |
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![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9 A5.2|9 24.84 cM | Start | 45,029,080 bp[2] |
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End | 45,041,368 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - middle temporal gyrus
- lateral nuclear group of thalamus
- cerebellar cortex
- cerebellar hemisphere
- prefrontal cortex
- right hemisphere of cerebellum
- cerebellar vermis
- superior frontal gyrus
- primary visual cortex
- right frontal lobe
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| Top expressed in | - lobe of cerebellum
- cerebellar vermis
- lateral geniculate nucleus
- olfactory tubercle
- superior colliculus
- medial geniculate nucleus
- habenula
- lateral septal nucleus
- lateral hypothalamus
- medial dorsal nucleus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PBB_GE_SCN2B_210363_s_at_fs.png/250px-PBB_GE_SCN2B_210363_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/1/17/PBB_GE_SCN2B_210364_at_fs.png/250px-PBB_GE_SCN2B_210364_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - voltage-gated sodium channel activity involved in cardiac muscle cell action potential
- sodium channel regulator activity
- sodium channel activity
- voltage-gated sodium channel activity
- voltage-gated ion channel activity
| Cellular component | - integral component of membrane
- voltage-gated sodium channel complex
- membrane
| Biological process | - chemical synaptic transmission
- nervous system development
- cardiac muscle cell action potential involved in contraction
- sodium ion transport
- sodium ion transmembrane transport
- regulation of sodium ion transmembrane transporter activity
- cardiac muscle contraction
- regulation of heart rate by cardiac conduction
- regulation of atrial cardiac muscle cell membrane depolarization
- membrane depolarization during cardiac muscle cell action potential
- regulation of ion transmembrane transport
- ion transport
- response to pyrethroid
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 11: 118.16 – 118.18 Mb | Chr 9: 45.03 – 45.04 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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