Толл-подобный рецептор 9 |
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Идентификаторы |
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Псевдонимы | TLR9, CD289, toll like receptor 9 |
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Внешние ID | OMIM: 605474 MGI: 1932389 HomoloGene: 68126 GeneCards: TLR9 |
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Расположение гена (Мышь) |
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![9-я хромосома мыши](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Хр. | 9-я хромосома мыши[2] |
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| Локус | 9|9 F1 | Начало | 106,099,797 bp[2] |
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Конец | 106,104,082 bp[2] |
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Паттерн экспрессии РНК |
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Bgee | Человек | Мышь (ортолог) |
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Наибольшая экспрессия в | - cerebellar hemisphere
- right hemisphere of cerebellum
- skeletal muscle tissue
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| | Дополнительные справочные данные |
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BioGPS | |
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Генная онтология |
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Молекулярная функция | - siRNA binding
- interleukin-1 receptor binding
- transmembrane signaling receptor activity
- 1-phosphatidylinositol-3-kinase activity
- гомодимеризация белка
- unmethylated CpG binding
- pattern recognition receptor activity
| Компонент клетки | - цитоплазма
- часть мембраны
- эндосома
- endoplasmic reticulum membrane
- мембрана
- early phagosome
- Golgi membrane
- клеточная мембрана
- внеклеточная область
- basolateral plasma membrane
- apical plasma membrane
- эндоплазматический ретикулум
- phagocytic vesicle
- endolysosome membrane
- лизосома
- endosome membrane
- цитоплазматическая везикула
- внеклеточное пространство
- endolysosome
| Биологический процесс | - positive regulation of interleukin-18 production
- positive regulation of toll-like receptor signaling pathway
- positive regulation of inflammatory response
- positive regulation of interleukin-12 production
- axonogenesis
- positive regulation of interleukin-10 production
- immune system process
- positive regulation of JUN kinase activity
- negative regulation of interleukin-6 production
- I-kappaB phosphorylation
- positive regulation of JNK cascade
- positive regulation of nitric-oxide synthase biosynthetic process
- MyD88-dependent toll-like receptor signaling pathway
- negative regulation of interleukin-8 production
- positive regulation of gene expression
- negative regulation of ATPase-coupled calcium transmembrane transporter activity
- negative regulation of toll-like receptor signaling pathway
- defense response to bacterium
- maintenance of gastrointestinal epithelium
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of interleukin-8 production
- positive regulation of interleukin-6 production
- positive regulation of tumor necrosis factor production
- positive regulation of I-kappaB kinase/NF-kappaB signaling
- positive regulation of chemokine production
- tumor necrosis factor production
- toll-like receptor 9 signaling pathway
- врождённый иммунитет
- воспалительная реакция
- response to molecule of bacterial origin
- negative regulation of NF-kappaB transcription factor activity
- положительная регуляция транскрипции РНК полимеразой II промотор
- передача сигнала
- positive regulation of interferon-beta production
- toll-like receptor signaling pathway
- phosphatidylinositol-3-phosphate biosynthetic process
- positive regulation of immunoglobulin production
- positive regulation of B cell proliferation
- regulation of toll-like receptor 9 signaling pathway
- positive regulation of MAPK cascade
- regulation of B cell differentiation
- positive regulation of B cell activation
- positive regulation of NIK/NF-kappaB signaling
- иммунный ответ
- I-kappaB kinase/NF-kappaB signaling
- defense response to virus
| Источники: Amigo, QuickGO |
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Ортологи |
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Вид | Человек | Мышь |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | |
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RefSeq (белок) | | |
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Локус (UCSC) | Chr 3: 52.22 – 52.23 Mb | Chr 9: 106.1 – 106.1 Mb |
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Поиск по PubMed | Искать[3] | Искать[4] |
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Информация в Викиданных |
Смотреть (человек) | Смотреть (мышь) |
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